The Outcome of Amniocentesis
at 14 Weeks of Gestation
Published: April 1, 2012 | DOI: https://doi.org/10.7860/JCDR/2012/.1925
Latika Narang, Alexandra Sawyer, Vaishali Garg, Onome Ogueh
PARTI CULARS OF CONTRIBUTORS:
1. MRCOG; Brighton and Sussex University Hospitals NHS
trust,
2. MSc; School of Psychology; University of Sussex,
3. MRCOG; Brighton and Sussex University Hospitals
NHS Trust,
4. MRCOG; Brighton and Sussex University Hospitals
NHS Trust,
NAME OF DEPARTME NT(S)/INSTITUTION(S) TO WHICH
THE WORK IS ATTRI BUTED:
Department of Obstetrics and Gynaecology
Princess Royal Hospital, Brighton and Sussex University
Hospital NHS Trust.
Correspondence
Dr. Latika Narang; 158,Winkworth Road, Banstead,
Surrey; SM7 2QT
Phone: 07961055723
E-mail: latikaong@yahoo.co.uk
Objective: To compare the safety and efficacy of amniocentesis at 14 weeks of gestation with amniocentesis at ≥15 weeks and chorionic villous sampling.
Method: This was a retrospective study of the pregnancy outcome of 299 women who underwent invasive prenatal diagnosis by using amniocentesis at 14 weeks of gestation, amniocentesis at ≥15 weeks of gestation and chorionic villous sampling. We compared the pregnancy outcomes and the complications in the 3 groups by using the Pearson’s χ2 test or the Fisher’s exact test.
Results: There was no significant difference between the women who underwent amniocentesis at 14 weeks of gestation and those who underwent amniocentesis at ≥ 15 weeks of gestation or chorionic villous sampling in terms of failed cultures, miscarriage, preterm pre-labour, rupture of membranes, preterm delivery and neonatal respiratory complications (p > 0.05).
Conclusion: Amniocentesis at 14 weeks of gestation is as safe as amniocentesis at ≥ 15 weeks of gestation and chorionic villous sampling.
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